2.0 Normal wound healing
- When the skin is damaged, the body will quickly establish its integrity to maintain haemostasis by forming a clot over the wound.
- The formation of the clot seals the wound and triggers an inflammatory response. This response involves the migration of white blood cells and growth factors to the wound.
- White blood cells and growth factors trigger the migration of other cells to the wound site to begin the process of healing.
- The clot and fibrin layers that have formed in the wound are eventually replaced by stronger tissue as fibroblasts migrate to the wound to produce collagen fibres.
- The formation of collagen and blood vessels provide fresh blood to the area which enables the wound to heal.
- Epithelial cells migrate from the sides of the wound to cover and form a new seal. Scar tissue never has the same strength as the original tissue that it has now replaced.